If you have a $2 bill burning a hole in your pocket, think twice before spending it at some store. The bill itself might be worth a lot more than two dollars — enough to build some serious wealth.

Certain $2 bills can fetch $4,500 and up on the collectibles market, according to the U.S. Currency Auctions (USCA) website. Just about all of the really valuable ones were printed in the 19 th ...