This study highlighted a secondary transport mechanism that relies on a membrane ... across cellular membranes using energy from ATP hydrolysis. Substrate-Binding Protein (SBP): A protein that ...
The neck region acts as a lever arm, amplifying the small conformational changes generated by ATP hydrolysis into larger movements. The tail domain is responsible for cargo binding and regulation of ...
The conserved head structure, the membrane portion and the peripheral stalk (or stalks) together could have formed a translocase that coupled ATP hydrolysis ... as a mechanism of enzyme evolution.
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