Neurofibrillary tangles (NFTs) are a hallmark of Alzheimer’s disease, formed by the accumulation of tau protein into fibrillar structures. These tangles, composed of paired helical filaments and straight filaments,

A breakthrough in the fight against Alzheimer's was made by researchers at the University of Pittsburgh, where a test was created to detect the disease in the brain earlier. Assistant Professor of Psychiatry Thomas Karikari is one of countless researchers nationwide working to combat Alzheimer's.