The 49ers and wide receiver Brandon Aiyuk got the worst news on his injured right knee. According to a report from Fox Sports ...

San Francisco 49ers star receiver Brandon Aiyuk will miss the rest of the season after tearing ligaments in his right knee.

NFL media appears to be at a loss for words regarding the San Francisco 49ers’ struggles in recent weeks. While there’s an overall agreement that the team is in a rough spot after the Niners ...

Has Brandon Aiyuk been getting open like he did last season? Yes, say San Francisco 49ers head coach Kyle Shanahan, Aiyuk and the analytics. In fact, one metric, which measures how much separation ...

For years, the San Francisco 49ers’ defensive line was easily the most feared part of an impenetrable defense. But for the second straight season, it’s a focal point of the team’s downward ...

WON members kicked off the season with 49ers team reporter Lindsey Pallares, NBC Sports Bay Area Insider Jennifer Lee Chan and 49ers Gold Rush member Marissa. In honor of the 50th anniversary of ...

The 49ers are about one second away from announcing their pets’ heads are falling off. A brutal collapse Sunday against the Rams led to an even bigger gut punch Monday with three notable injury ...

Watson left Sunday’s win over the 49ers with an ankle injury and did not return. The news does not appear good for Watson. “I think Jaylen will be out long term,” Reid said, via Pete Sweeney of ...

This will sting a bit. Wide receiver Jauan Jennings will not be available when the San Francisco 49ers face the Kansas City Chiefs. He is dealing with a hip injury he sustained in the 49ers' Week ...

For most of Shanahan’s tenure in the Bay, the San Francisco 49ers have owned his buddy Sean McVay’s club. SoFi Stadium on Sunday was, again, a sea of red. The hosts were winless and coming off ...

Christian McCaffrey’s injury status is even worse than once thought. 49ers head coach Kyle Shanahan confirmed Monday that the star running back is dealing with Achilles tendinitis in both of his ...

SANTA CLARA – Fred Warner’s interception return delivered the 49ers’ first touchdown of Sunday’s triumph, and a cinematic goal-line dive completed a highlight-reel play by the NFL’s most ...