At an up-and-down 3-4, the reigning NFC champion San Francisco 49ers can't be reliably counted on as a bona fide contender.

Aiyuk’s absence adds to the injuries of Jauan Jennings, Deebo Samuel, and Christian McCaffrey, other key players in San ...

The San Francisco 49ers and fantasy football managers won't have star wide receiver Brandon Aiyuk at their disposal anytime ...

The 49ers need to make a move to address their wide receiver situation after Brandon Aiyuk's ACL & MCL tear.

The San Francisco 49ers calculus at the trade deadline may have changed following a season-ending ACL injury for star wide ...

On Monday, San Francisco 49ers wide receiver Deebo Samuel expressed his support for his injured teammate, Brandon Aiyuk. Head ...

An all-too-familiar story played out for the San Francisco 49ers at Levi's Stadium on Sunday, as they once again wound up not ...

San Francisco 49ers wide receiver Brandon Aiyuk suffered a torn ACL Sunday against the Chiefs. Here, I look at five options ...

Talanoa Hufanga, an All-Pro safety in 2022, has played in just one game after recovering from a torn ACL, was felled by a ...

The San Francisco 49ers were hit with a double dose of rough health news regarding two wide receivers on Monday.

San Francisco 49ers wide receiver Brandon Aiyuk was carted to the locker room after suffering a leg injury in their game ...

The San Francisco 49ers wide receiver sustained a season-ending knee injury in their 28-18 loss to the Kansas City Chiefs on ...