The North Carolina knockout mouse (Cftr tm1Unc) line: Contain a Neo cassette in exon 10 of the murine Cftr gene and exhibit a severe phenotype ... conduct thorough histopathologic analyses of airway ...
The CFTR gene was identified in 1989 ... Structural GenomiX accepted $11 million over five years to solve the structure of CFTR, with additional payments along the way for reaching critical ...
in addition to maintenance of wild-type Sprague Dawley strain for additional use Generation and procurement of novel relevant CF animal models to understand newly developed CFTR modulators, and to ...
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