For example, prokaryotic organisms have sensors ... When a signaling molecule joins with an appropriate receptor on a cell surface, this binding triggers a chain of events that not only carries ...

Almost 35% of drugs approved by the Food and Drug Administration work by targeting G protein-coupled receptors (GPCRs), proteins embedded in cell membranes that allow cells to communicate with ...

For example, beta cells secrete insulin in ... through these receptors is disrupted in diabetes. Many classes of cell surface receptors exist, the largest of which is the GPCR family.

to target a cell-surface receptor called DR5 (death receptor 5) that many tumor cells have. When activated, DR5 can trigger the death of these cells by a self-destruct process called apoptosis.

Engineered immune cells called CAR-T cells are used in the treatment of cancer. Researchers from Uppsala University have now ...

“It will be very interesting to find out if this class of molecules in the nervous system just modulates neurotransmitter receptors, or whether they regulate other cell surface receptors ... Heintz ...