So far, one aptamer drug that binds to vascular endothelial ... secondary structures and targets in the coagulation cascade (factor IXa and factor Xa) could both be inactivated by protamine.

Vitamin K antagonists, such as warfarin, have an unpredictable pharmacokinetic profile and numerous food and drug interactions ... key proteases in the coagulation cascade: thrombin and factor ...

and initiate the activation of the coagulation cascade when they come into contact with blood. Analyses by the study authors confirm that mucosal bleeding in the mouth of these patients is indeed ...

A recent study provides new insights into the mechanisms of coagulation in persons with haemophilia A, the most common form of haemophilia. The research team was able to show that saliva contains ...