In mitosis, two cells called daughter cells are produced, each identical to the parent cell. When looking at cells with a microscope, the length of different stages of the cell cycle can be ...
Apart from those with a clearly regulatory role, many proteins have important functions ... end of mitosis and on the condensation and decondensation of chromatin. How does the cell cycle affect ...
While the intricate dynamics of mitosis is well-studied in the so-called somatic cells – the cells that have a specialized function ... that re-enter the cell cycle quickly succumb to senescence ...
One road block to understanding the mechanism was that disruption of the Ran GTPase cycle has a vast impact ... artificial beads to prove the direct function of Ran GTPase in NE assembly.
The goal of my research is to understand the biogenesis of centrioles/centrosomes and primary cilia, and how defects in these processes affect mammalian cell physiology and evoke stress responses.