Patients with cystic fibrosis produce a faulty version of the CFTRexternal ... To find out, the researchers measured how much acid was secreted by airway cells from healthy humans, pigs, and mice.

Bi-transgenic mice developed using this knockout line that are available include: FABP-hCFTR mice: Express a wild type human CFTR transgene from the intestine-specific FABP promoter on a Cftr tm1Cam ...

Two independent research teams have used single-cell RNA sequencing to generate detailed molecular atlases of mouse and human airway cells ... that expresses high levels of the gene mutated in cystic ...

Cystic fibrosis is caused by a recessive allele ... They found that most of the mice that lived on this rock were black in colour. Explain how the population of mice in this area became mostly ...