Endocytosis occurs when the cell membrane engulfs particles (dark blue) outside the cell, draws the contents in, and forms an intracellular vesicle called an endosome. This vesicle travels through ...

These include some obvious mechanical activities such as endocytosis, cell motility and membrane resealing, but also others, such as replication and transcription. Taking the motor proteins as an ...

Endocytosis and degradation of the membrane receptors in the lysosome controls the activation of intracellular signaling pathways, but the mechanisms that control the endocytosis itself are largely ...

A new study shows how an anticancer drug triggers an "outside in" signal that gets it sucked into a cancer cell. The work, ...

But they didn’t know why. From prophase to anaphase, shallow clathrin-coated pits form at the plasma membrane, but the cell never internalizes them. Two main theories have tried to explain how ...

Each cell is separated from its environment by a barrier called a cell membrane that protects the cell from the outside environment. However, this barrier can be overcome by certain chemicals that ...

In our lab, we focus on clathrin-mediated endocytosis, the predominant route for membrane internalisation in most cells. In addition to its role in endocytosis, the clathrin machinery also forms ...

Some larger cargo, such as membrane proteins, nutrients, and pathogens, enter the cell via a process known as clathrin-mediated endocytosis. To gain a deeper understanding of this important ...

The axon initial segment (AIS) is where nerve signals begin, and its adaptability is key to brain function. Scientists have found that the AIS changes in response to activity levels, helping neurons ...

membrane structure and function, cell adhesion, intercellular communication, signal transduction, chemotaxis, receptor-medicated endocytosis and intracellular trafficking. Mechanisms underlying ...

Functions of membrane microdomains on the endocytic pathway: integration of endocytosis and signalling We are interested ... for the uptake of a wide variety of cargo. Using live-cell microscopy we ...

A new study shows how an anticancer drug triggers an “outside in” signal that gets it sucked into a cancer cell.