Rice lab pioneers an assembly kit for synthetic sense-and-respond circuits in human cells. Rice University bioengineers have ...

In multicellular organisms, growth factors, hormones, neurotransmitters, and extracellular matrix components are some of the many types of chemical signals cells use. These substances can exert ...

Using AI, Jahed, Rahmani and colleagues developed a method to correlate extracellular signals with specific intracellular signals. To develop the new method, the team first engineered an array of ...

A range of extracellular and intracellular signals can trigger either cell growth or apoptosis. When cells receive these signals from their neighbors or from other aspects of the external ...

While extracellular signals can be captured with less invasive methods, they do not provide much detail about the cell's electrical activity. "It is like listening to a conversation through a wall ...

Phosphorylation is involved in a wide range of cellular functions, including the conversion of extracellular signals into intracellular responses—e.g., moving, secreting a substance, reacting to ...

Comparison of methods to record signals inside cells. Current methods (left) are more costly, invasive and low-throughput. The new method (right) overcomes these hurdles by using AI to reconstruct ...