Chelico's lab studies immune responses to HIV, particularly a family of proteins called APOBEC3 which cause mutations in the HIV virus. Her research and others' show that the virus uses a ...

The HIV-1 capsid is formed by a mesh of around 200 protein hexamers and pentamers, arranged similarly to a football. It is, however, not spherical, but shaped like a cone, with a narrow and a ...

Among many of the viral offensive strategies, HIV-1 viral auxiliary proteins (Tat, Rev, Nef, Vif, Vpr and Vpu) play important roles in the host-pathogen interaction and thus have significant ...

HIV-1, like other viruses, lacks the machinery to produce its own proteins and must rely on the host cell to translate its genetic instructions. After entering host cells, it seizes control of the ...

A Brisbane man who took part in the University of Queensland’s aborted Covid vaccine trial is still returning “false positive” HIV tests four years later.

some of the antibodies were not binding directly to the HIV viral antigen, but to immune molecules on its surface. "These antibodies actually make no direct contact with the viral protein," says ...

Recent studies showed that a peptide, the protein transduction domain (PTD) from HIV Tat, could improve the distribution of cytoplasmic reporter proteins when administered systemically as fusion ...

GSK is prioritizing development of its hepatitis B treatment bepirovirsen as the pharma ends work on another potential ...

rather than the HIV virus alone (gray). LA JOLLA, CA—Many vaccines work by introducing a protein to the body that resembles part of a virus. Ideally, the immune system will produce long-lasting ...

TAT is a nonstructural HIV protein of 86-101 amino acids that is made up of two exons. The largest part of the protein derives from the first exon and acts as a transacting nuclear regulatory ...

It is then activated when our cells turn DNA into proteins — a process called transcription and translation — and it's one that we need for life. HIV piggybacks this process. And our cells ...

some of the antibodies were not binding directly to the HIV viral antigen, but to immune molecules on its surface. "These antibodies actually make no direct contact with the viral protein," says ...