Eric Sorscher and colleagues at UAB developed two different ways to overcome the genetic mutations responsible for cystic fibrosis. Cystic fibrosis is a hereditary disease caused by mutations in a ...

New study suggests why mice with cystic fibrosis mutations can stave off bacterial infections in their lungs. People who have cystic fibrosis are susceptible to bacterial infections in their lungs.

CF often arises from mutations that make the cystic fibrosis transmembrane conductance regulator (CFTR) protein misfolding and malfunction, causing thick mucus to aggregate in the lungs while also ...

These engineered tRNAs have shown promise in restoring the function of proteins affected by nonsense mutations, particularly in the cystic fibrosis transmembrane conductance regulator (CFTR ...

My dad tells me that my Uncle Andy was the greatest of kids. He was always smiling, had the vocabulary and sharpness of a literary maestro, and loved exploring. He also never complained a day in his ...

As Healio previously reported, the FDA recently approved Alyftrek for patients aged 6 years and older with cystic fibrosis with certain mutations based, in part, on data from these trials ...

While many are harmless, some are known to be involved in diseases, including cystic fibrosis ... 57% of missense mutations cause no harm, while around a third (32%) may be harmful, and the ...