THE term "hepatic ... and ammonia metabolism will help to clarify some of the existing confusion. Two facts seem apparent: ammonia intoxication is a specific entity in "exogenous" encephalopathy ...

A cerebral intoxication ... To resolve the question of a hepatic component in the metabolic encephalopathy, a provocative load of ammonium chloride was administered by mouth, and after 12 gm.

This can cause dangerous levels of ammonia to travel to the brain and cause hepatic encephalopathy, which impairs cognitive function, causes confusion and delirium and can sometimes lead to a coma ...

Hepatic encephalopathy is caused by the accumulation of gut-derived toxic substances, such as ammonia, in the bloodstream that are normally removed by the liver. Treatment usually consists of ...