Subtle signs of neurodegeneration can be detected in blood, CSF, and neuroimaging, up to 20 years before the motor symptoms ...
In the early-stage Huntington's disease group, significant increases in the putamen and globus pallidus were observed; reductions in functional anisotropy included the internal capsule ...
Researchers have detected early changes in brain scans and biomarkers in young people with the Huntington’s disease gene, 20 ...
If you’ve ever heard of Huntington’s disease, you know how devastating it can be. This hereditary brain disorder slowly robs ...
Huntington's disease (HD) is a hereditary neurodegenerative disorder ... Both chorea and impairment of voluntary movements progress in the middle stages of the disease, but later, chorea may gradually ...
One proposes to use embryonic stem cells, mature them into early forms of those nerve cells and ... San Diego RNA-directed therapy for Huntington’s disease Quest – Discovery Stage Research Projects $1 ...
Aims To assess hippocampal-dependent spatial memory and perception in pre-manifest and early stage Huntington’s disease (HD) patients. Background Huntington’s disease (HD) is an autosomal ...
Subtle changes in the brain, detectable through advanced imaging, blood and spinal fluid analysis, happen approximately twenty years before a clinical motor diagnosis in people with Huntington's ...
Objectives: To analyse grey matter changes in early stages of Huntington’s disease using magnetic resonance imaging (MRI) and the technique of voxel based morphometry (VBM). Methods: Forty four ...
A cure for Huntington’s disease may be a step closer after a study found brain changes linked to the condition could be detected 23 years before a diagnosis. Symptoms of the inherited disease ...
Subtle changes in the brain, detectable through advanced imaging, blood and spinal fluid analysis, happen approximately twenty years before a clinical motor diagnosis in people with Huntington’s ...
More information: Anat Bahat et al, Lowering mutant huntingtin by small molecules relieves Huntington's disease symptoms and progression, EMBO Molecular Medicine (2024). DOI: 10.1038/s44321-023 ...