Systemic lupus can be mild or severe. Cutaneous lupus erythematosus This form of lupus is limited to the skin and can cause many types of rashes and lesions. Drug-induced lupus erythematosus This is a ...

Specific and nonspecific rashes associated with antibodies to Ro/SS-A are often related to subacute cutaneous lupus erythematosus (SCLE). Typically, lesions specific to SCLE do not itch and may ...

Males with lupus nephritis had higher all-cause mortality and proportion of infection-related death compared to females.

People with lupus often need to use medicines to manage their symptoms. Although there are many oral medicines that treat lupus, some people with more severe symptoms may not get enough benefit ...

Lupus in the classical period (1230-1856) The history of lupus during the classical period was reviewed by Smith and Cyr in 1988. Of note are the derivation of the term lupus and the clinical ...

for example discoid lupus erythematosus (DLE). Caproni and colleagues, therefore, studied the expression of CD40 and CD40L in skin lesions of patients with SCLE. The authors conclude that the CD40 ...

Tobias Alexander, MD, and colleagues at Charité-Universitätsmedizin Berlin tried it in a female patient, age 23, with ...

Immune cells called monocytes produce a key inflammatory protein called interleukin-1 beta (IL-1β) through an unconventional pathway in patients with systemic lupus erythematosus, commonly referred to ...

1. Cervera R, Khamashta MA, Font J, et al.: Systemic lupus erythematosus: clinical and immunologic patterns of disease expression in a cohort of 1,000 patients. The European Working Party on ...

Accordingly, NIM-1324 is a prime candidate for a first-in-class oral therapeutic in the treatment ... from systemic lupus erythematosus (SLE) patients and provided protection from clinical disease ...

The drug is being tested in patients with the most common form of lupus, systemic lupus erythematosus, where the patient's immune system attacks the body's own tissues and potentially leads to ...