"Given the high conservation of TGF-β signaling, manipulating TGF-β pathways to coordinate mitochondrial stress responses and ...

Studies show cell-free DNA (cfDNA), including cf-nDNA and cf-mtDNA, is released during stress, offering a potential biomarker ...

Although previous work had indirectly suggested that changing mitochondrial function affected lifespan, “this is the first clear demonstration [that it] extends mouse lifespan,” Miller added. It’s ...

As a team we are dedicated to improve the life of patients with mitochondrial disease by understanding the mechanisms underlying these maladies that have no treatment option to date.

Mitochondria do far more than produce energy ... Numtogenesis may serve to speed up evolution as a response to stress. Most importantly, given that people with more numts in their brain die ...

Whether cells in the human body survive or die under stress depends ... Instead, the mitochondria activate mechanisms that trigger an inflammatory response, which puts the tissue on alert and ...

“This is a straightforward and clear story,” said Cole Haynes, who studies mitochondrial dysfunction at Memorial Sloan Kettering Cancer Center ...

Mitochondria are crucial organelles for cellular homeostasis, regulating processes such as ATP production, reactive oxygen species (ROS) management and Ca2+ signaling.

the role of NAD+ metabolism in mitochondrial diseases and its curative effect and mitochondrial stress response, especially in a tissue-specific manner. I am a mom to two small kids and love spending ...