The incidence of calcium oxalate nephrolithiasis in the US has been increasing throughout the past three decades. Biopsy studies show ... of the ion in general and renal physiology.

Many patients with multiple myeloma develop renal failure, often owing to light chain cast nephropathy. Although several randomized trials have examined the efficacy of plasma exchange for cast ...

Immunosuppressive therapy is effective against IgA nephropathy ... and age at biopsy to be the main risk factors for development of end-stage renal disease. A clinical predictive index (CPI ...

Recent investigations indicate, however, that oxalate can increase chloride, water, and sodium reabsorption in the proximal tubule and activate multiple signaling pathways in renal epithelial cells.