Cirrhosis is the severe scarring or fibrosis of the liver. It happens in the late stage of liver disease and ... Institutes of Health (NIH), about 1 in 400 adults are living with cirrhosis in ...

The exact stage at which fibrosis/cirrhosis becomes truly irreversible ... for fibrotic diseases of many organs, including liver. [1] The following article describes in greater detail the cellular ...

As noted above, stellate cell activation is the central event in hepatic fibrosis. Activation consists of 2 major phases: (1) initiation (also called apreinflammatory stage) and (2) perpetuation ...