Intestinal stem cells are multipotent adult stem cells, which in mammals reside in the base of the crypts of the adult intestine. Intestinal stem cells continuously self-renew by dividing and ...

More information: Jaakko Mattila et al, Stem cell mTOR signaling directs region-specific cell fate decisions during ...

so stem cells must create replacements. What's really remarkable about the intestinal lining is how big it is. If we were to filet open your intestine and lay it flat, it would cover the surface ...

These components of the small intestine would need to be generated ... Although cell-based therapy such as hematopoietic stem cell transplantation has been practiced for decades, the use of ...

We spatiotemporally pattern these cues using photoinduced degradation, viscoelasticity, and bond formation to study how intestinal stem cell colonies respond to alterations in geometric confinement, ...

Figure caption, The properties and functions of stem cells in animals Some locations in the adult body, such as the lower layers of the skin and small intestine, still contain populations of stem ...

The authors examine the role of Numb, a Notch inhibitor, in intestinal stem cell self-renewal in Drosophila during homeostasis and regeneration. This is an important study providing evidence of a Numb ...

How does a stem cell know its position in a tissue ... with machine learning based segmentation algorithms to model the full cellular content of the fly intestine. Together with our newly developed ...