Although this approach has met with limited success for such genes as CFTR, which encodes the cystic fibrosis transmembrane ... a large gene by the split AAV vectors through heterodimerization.

More recent deep-learning approaches have used dense embeddings learned ... document retrieval in the medical domain of cystic fibrosis, that both of these models perform roughly equivalently. Notably ...

Experiments and modeling reveal the unexpected structure that can be seen in bacteria grown in mucus samples and biofilms.

Lentiviral vectors ... used, and assays to assess the correction of surfactant production and function. This work was supported by the National Institutes of Health (UG3 HL147366, P01 HL51670, P01 ...