Here's an early look at some predictions and picks to win the AFC, NFC and which team will be the Super Bowl 59 champion.

The Buffalo Bills have won over fans, national media members and computer automation. Buffalo will win Super Bowl 59, ...

The Cleveland Browns have won many championships as a franchise but no Super Bowls. Cleveland won a championship in its ...

The Bills gained 559 yards, the most in the McDermott era and tied for the fifth most in club history. James Cook rushed for ...

Allen is playing the best football of his career, with 36 combined touchdowns and only seven turnovers for the AFC East ...

The Detroit Lions got back in the win column and stand alone as the favorite to win the Super Bowl, just ahead of the Bills ...

Stacker compiled a ranking of the biggest preseason underdog teams that won the Super Bowl using data from Pro Football ...

ESPN's Benjamin Solak put New England Patriots QB Drake Maye ahead of Washington Commanders QB Jayden Daniels in rookie ...

The NFC-leading Detroit Lions are playing the AFC East-leading Buffalo Bills in a marquee, late-season matchup that might be ...

The Buffalo Bills are heading into their Week 17 AFC East showdown against the New York Jets with a 12-3 record. They are ...