This valuable study is a detailed investigation of how chromatin structure influences replication origin function in yeast ribosomal DNA, with a focus on the role of the histone deacetylase Sir2 and ...
Data presented in this useful report suggest a potentially new model for chemotaxis regulation in the gram-negative bacterium P. putida. Data supporting interactions between CheA and the ...
Upping AMPK. In response to calorie restriction, LCA binds TULP3, activating sirtuins and triggering deacetylation of lysines on the V1E1 subunit of the lysosomal V-ATPase. This slows the proton pump, ...
A rare genetic disorder affecting copper levels in the body, Menkes disease is caused by mutations in the ATPase Copper Transporting Alpha (ATP7A) gene. Give your business an edge with our leading ...
They found that when the animals' fat cells began overproducing GIPR, they had increased activity in sarco/endoplasmic reticulum calcium ATPase (SERCA ... extra ATP—a molecule used for energy ...
The P382S mutation of LRD6-6 in spl-A impairs its ATPase activity and disrupts its interaction with ESCRT-III subunits OsSNF7.1/7.2/7.3 In summary, our study reveals that the conserved amino acid ...
Attempts to design small molecule therapies directed to this cytokine have not led to approved products yet. Here we report the discovery and development of a potent small molecule inhibitor of TNF ...
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