Denali: Despite ALS Primary Endpoint Failure, Possible Path Forward Remains
Denali Therapeutics Inc.'s stock remains stable despite trial setback in ALS. BLA filing for MPS II treatment on track. Click ...
BioSpace17h
HEALEY ALS Trial Serves Up More Disappointment as Denali, AbbVie/Calico Fail
Misses from amyotrophic lateral sclerosis hopefuls Denali Therapeutics and partners AbbVie and Calico Life Sciences mark the ...
Science Daily2d
Potential new therapeutic targets for Huntington's disease
A research team has discovered intricate molecular mechanisms driving the RNA processing defects that lead to Huntington's disease and link HD with other neurodegenerative disorders such as ...
IBN Coverage: Clene (NASDAQ: CLNN) Receives FDA Roadmap on Potential Accelerated Pathway for CNM-Au8(R)
This article was published by IBN, a multifaceted communications organization engaged in connecting public companies to the ...
Hosted on MSN1d
DNLI's Hunter Syndrome Drug Gets Breakthrough Therapy Designation
Denali Therapeutics Inc. DNLI announced that the FDA has granted Breakthrough Therapy Designation to its pipeline candidate, ...
FierceBiotech3d
Rival AbbVie and Denali prospects flunk phase 2/3 ALS tests, denting hopes for shared mechanism
AbbVie, Calico and Denali Therapeutics’ hopes of treating amyotrophic lateral sclerosis (ALS) by targeting eIF2B have all ...
Discovery of molecular mechanisms offers new targets for Huntington's treatment
A University of California, Irvine-led research team has discovered intricate molecular mechanisms driving the RNA processing ...
Outsourcing-pharma3d
Denali Therapeutics’ ALS drug fails to improve function and survival in phase 2/3 trial
Denali Therapeutics' DNL343 fails to slow ALS progression in phase 2/3 trial but shows safety and offers insights for future ...
Pharmaceutical Technology11d
Monepantel by Neurizon Therapeutics for Amyotrophic Lateral Sclerosis: Likelihood of Approval
Monepantel is under clinical development by Neurizon Therapeutics and currently in Phase II for Amyotrophic Lateral Sclerosis.
Neurology Advisor8h
Lower Risk of ALS Seen for Men With High Levels of Physical Activity, Fitness
For men, high levels of physical activity and fitness are associated with reduced risk of amyotrophic lateral sclerosis (ALS).
News Medical on MSN1d
Researchers uncover molecular mechanisms driving RNA processing defects in Huntington's disease
A University of California, Irvine-led research team has discovered intricate molecular mechanisms driving the RNA processing defects that lead to Huntington's disease and link HD with other ...