Amyotrophic lateral sclerosis (ALS ... More information: Swift Induction of Human Spinal Lower Motor Neurons and Robust ALS Cell Screening via Single-Cell Imaging, Stem Cell Reports (2024).

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Amyotrophic lateral sclerosis (ALS) is a fast-progressing neurodegenerative disease with an average survival time of three years. In ALS, certain types of neurons called motor neurons that are ...

The bioenergetic deficits observed in Amyotrophic Lateral Sclerosis result from the disruption of mitochondria-associated ER membranes. Here, the authors show that this disruption impairs the use ...

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder ... 3 While the split-hand phenomenon is more commonly observed in spinal-onset ALS, it is also observed in bulbar onset ...

Background Corticospinal tract (CST) degeneration and cortical atrophy are consistent features of amyotrophic lateral sclerosis (ALS). We hypothesised that neurite orientation dispersion and density ...

Journal of Nuclear Medicine December 2024, jnumed.124.268343; DOI: https://doi.org/10.2967/jnumed.124.268343 ...

It is unclear whether PMA is simply a clinical phenotype of amyotrophic lateral sclerosis (ALS) in which upper motor neuron ... from the left hemisphere), hippocampus, brainstem and spinal cord. In ...

Specialists diagnose amyotrophic lateral sclerosis (ALS) twice as fast as general neurologists ... In the year leading up to an ALS diagnosis, patients received a mean of 1.5 brain MRIs, 1.6 spine ...

Tech-driven revolution is dramatically changing healthcare provision, reshaping how we diagnose, treat and prevent diseases ...