Neurology Advisor3h
Lower Risk of ALS Seen for Men With High Levels of Physical Activity, Fitness
For men, high levels of physical activity and fitness are associated with reduced risk of amyotrophic lateral sclerosis (ALS).
BioSpace12h
HEALEY ALS Trial Serves Up More Disappointment as Denali, AbbVie/Calico Fail
Misses from amyotrophic lateral sclerosis hopefuls Denali Therapeutics and partners AbbVie and Calico Life Sciences mark the ...
Denali: Despite ALS Primary Endpoint Failure, Possible Path Forward Remains
Denali Therapeutics Inc.'s stock remains stable despite trial setback in ALS. BLA filing for MPS II treatment on track. Click ...
Business Weekly22h
Alchemab gilds the Lilly with lucrative ALS alliance
Biopharma innovator Alchemab Therapeutics, whose labs are in Cambridge UK, is collaborating with multinational pharma giant ...
ALS News Today1d
DNL343, fosigotifator fail HEALEY platform trial’s main goal in ALS
DNL343 and fosigotifator are made to activate the ISR pathway protein eIF2B, but both failed to slow ALS progression in the ...
Science Daily1d
Potential new therapeutic targets for Huntington's disease
A research team has discovered intricate molecular mechanisms driving the RNA processing defects that lead to Huntington's disease and link HD with other neurodegenerative disorders such as ...
ALS News Today2d
Number of US ALS cases expected to increase 10% this decade: Study
The number of ALS cases in the U.S. is expected to increase by over 10% by 2030, as compared with 2022 prevalence rates, per ...
EurekAlert!3d
Patient-derived induced pluripotent stem cell organoids for amyotrophic lateral sclerosis drug discovery
Announcing a new publication for Acta Materia Medica journal. Complex biological mechanisms and unidentified therapeutic targets for amyotrophic lateral sclerosis (ALS) significantly hinder the develo ...