Bone marrow plays a crucial role in maintaining hematopoietic stem cells and bone homeostasis. However, research has been ...

Frizzled (FZD) proteins are the principal receptors of the Wnt signaling pathway. However, whether Wnt ligands induce FZD endocytosis and degradation remains elusive. The transmembrane E3 ubiquitin ...

Researchers have developed a new microscopic method to observe the interactions of therapeutic antibodies with target molecules on tumor cells.

ImmuneOnco announced dosing of first patient in its recently initiated Phase 1b/2 clinical trial of IMM2510/SYN-2510 in combination with ...

Thanks to an innovative method of super-resolution microscopy, researchers observed with molecular resolution in 3D how therapeutic antibodies attack and alter B cells, thereby inducing their ...

Professor Markus Sauer from the Biocentre of Julius-Maximilians-Universität (JMU) Würzburg in Bavaria, Germany ...

In blood cancers such as chronic lymphocytic leukemia, B cells of the immune system multiply uncontrollably. One form of ...

In December 2024, NextCure announced that the U.S. Food and Drug Administration had cleared its Investigational New Drug application for LNCB74. LNCB74 is being developed in partnership with LigaChem ...

No writing assistance was utilized in the production of this manuscript. Monoclonal antibodies are novel therapeutic agents used with great success in the treatment of rheumatoid arthritis (RA).

Livalo has interactions with some other drugs. Examples include other cholesterol-lowering drugs, such as gemfibrozil (Lopid). An interaction occurs when one substance causes another substance to ...

The basic principles of an Enzyme-linked Immuno Sorbent Assay kit are: Antigen-Antibody Interactions: The specific chemical affinity interaction occurs between the antigen and antibody in ELISA kits.