Our guts are home to trillions of bacteria, and research over the last few decades has established how essential they are to ...

The model has uncovered a hidden layer of molecular code that shapes biological organization, adding new dimensions of ...

Researchers at the University of Liège (Belgium) have uncovered a previously unknown mechanism that regulates the immune ...

Inflammatory bowel diseases (IBDs), which include ulcerative colitis (UC) and Crohn’s disease (CD), are chronic conditions ...

Finally, PI3K/Akt is a key signaling pathway known to regulate apoptosis in intestinal epithelial cells, and it is expected to explain the mechanism by which Cyn ameliorates intestinal epithelial ...

Chimeric antigen receptor-T (CAR-T) cell therapy, initially successful in hematologic malignancies, presents a promising avenue for treating solid tumors, including CRC. This review explores the ...

Loss of FOXG1 in postmitotic neurons non-autonomously enhances gliogenesis in the progenitors via FGF signalling. These results fit well with the model that newborn neurons secrete cues that trigger ...

A Brock-led research team has discovered a mechanism that provides new insights into stopping the spread of various cancers by controlling a stage of cell signalling, a process through which cells ...

Overall, the results will be of interest to both the fields of 3D genome architecture and pediatric ... 2015) on all ATAC-seq-defined OCRs for each cell type. We assessed cell-type-specific enrichment ...