With the latest injury to WR Brandon Aiyuk, the 49ers will have to find ways to win using their depth players.

The San Francisco 49ers can hardly afford any more offensive injuries. Running back Christian McCaffrey has been out for the ...

San Francisco 49ers star receiver Brandon Aiyuk will miss the rest of the season after tearing ligaments in his right knee.

The 49ers and wide receiver Brandon Aiyuk got the worst news on his injured right knee. According to a report from Fox Sports ...

The world's richest turf race wound up in a thrilling finish, potential stars shone in Japan and Hong Kong and British ...

San Francisco 49ers wide receiver Brandon Aiyuk was carted to the locker room after suffering a leg injury in their game ...

(Photo by Jack Gorman/Getty Images) Brandon Aiyuk, WR, San Francisco 49ers The 49ers' co-WR1 became a bit of a "drama king" during a contentious contract negotiation that resulted in a four-year ...

Although Aiyuk eventually got what he wanted in securing the blockbuster contract, he has continued to sulk and pout after scribbling his name on a pact that made him one of the highest-paid ...

Brandon Aiyuk is only a month removed from signing a four-year, $120 million deal that makes him almost untradeable. Unloading him would yield $18.4 million in dead money in 2025 and $5.5 million ...

Brandon Aiyuk is only a month removed from signing a four-year, $120 million deal that makes him almost untradeable. Unloading him would yield $18.4 million in dead money in 2025 and $5.5 million ...

MILWAUKEE — If Brandon Nimmo had some help with his ninth-inning single, he knows where it came from. In a celebratory and raucous clubhouse after the comeback, 4-2 Mets win over the Brewers at ...

It's just not the one you might expect. Unlike many of the other 49ers' top skill position players, wideout Brandon Aiyuk has been healthy and available in all four of San Francisco's games.