These names in the biotech sector are seeing a substantial increase in search activity today, as determined by InvestingChannel. They ...
Alternatively, given that the target for these new anti-mitotics is only expressed during mitosis, in clear distinction to tubulin, which has important functions outside the cell cycle including ...
Gygi's group looked at phosphorylation changes across the proteome in the mitotic and G 1 phases of the HeLa cell cycle, using stable ... accompanied mitosis. “We were absolutely amazed; there ...
In a promising development for cancer treatment, researchers have pinpointed a new target by activating a DNA repair enzyme known as Tyrosyl-DNA phosphodiesterase 1 (TDP1).
that play various roles in the regulation of MT dynamics during the cell cycle and differentiation, as well as in response to MT-antagonistic drugs. These proteins are also capable of modulating MT ...
The Phase 1 dose escalation part of the study enrolled a total of 48 unselected, all comer patients with advanced solid tumors and lymphoma who were treated with oral fadra as monotherapy. Recommended ...
Calcineurin fine tunes the balance between proliferation and differentiation of Notch-responsive progenitors in the pancreatic ducts to enable beta cell regeneration in zebrafish.
A centromere is a specialized location in the DNA that functions as the control center of cell division and is maintained, unchanged, across generations of cells. It is characterized by a special ...
The study addresses the complex regulation of HSCs, highlighting p21's multifunctional nature beyond cell cycle control. Through the use of p21-tdTomato mice, researchers differentiate between p21 ...
New study shows that the lengths of menstrual cycles, follicular phases (before egg release) and luteal phases (after ovulation) are all variable. The luteal phase is importantly more variable than ...
For example, soft cells could shed light on a type of cell expansion called tip growth, which is widely used in nature, such as by algae and fungi. The conditions that lead to soft tiling could ...