One key player in this intricate process is the nucleolus, a spherical structure that sits inside the cell's nucleus, the compartment where gene expression is orchestrated and performed.

Toronto scienists have made a groundbreakign discovery that early human development is regulated not by our own genes but by “selfish DNA” that spreads around the genome. For years, scientists ...

cerevisiae. While these studies continue, we will use that knowledge to investigate the normal organization of the nucleolus in human cells and its perturbations in malignancy. Lin, S, Rajan S, ...

The images show the inside of the cell nucleus at an 8-cell stage (left) and at a later stage (right).  Chromosome 19 is shown in red whereas the nucleolus containing the gene-silencing machinery is ...

in the nucleolus, enabling sol-gel transitions in which materials shift between fluid-like and gel-like states, and controlling chemical reactions within the cells. Inspired by these unique ...

Results suggest novel roles for LINE1 transposable elements that can be explored in the contexts of diseases, from ...

In a discovery that sheds light on the complex mechanisms of gene regulation, scientists at EPFL have uncovered a critical role for the protein ZNF274 in keeping certain genes clusters turned off by ...

Transposons, specifically LINE-1 elements, previously regarded as genomic parasites, play a pivotal role in early human ...