Here we explore peptide inhibitors of Cdc20, a substrate-recognition subunit and activator of the E3 ubiquitin ligase the anaphase promoting complex/cyclosome (APC/C) that is essential in mitosis and ...

but there is no atypia (structural cellular abnormalities). This has increased risk but patients are only suggested close follow-ups and 6-month ultrasound follow-ups. Also, we should remember that ...

The clinical and pathological features of 29 cellular blue nevi (CBN ... fascicular or neuronevoid, and atypical varieties. One case developed a benign nodal metastasis. In one case, malignancy ...

Johnson & Johnson will pay US$14.6 billion to acquire Intra-Cellular Therapies. The deal provides J&J with an FDA-approved atypical antipsychotic as well as a pipeline of therapies for diseases of ...

A Legend, on DVD, Blu-ray and digital video-on-demand Jan. 21, isn't always successful, but is an atypical film for Chan that ultimately pays off. A Legend opens in the Han and Hun era ...

monitoring the effectiveness of chemopreventive agents as evidenced by regression of cellular atypia, and delivering drugs directly into the ducts. At present, however, ductal lavage remains ...

Mild cellular atypia was noted, with a nuclear grade of 1–8/10 HPF. The excised tissue was fragmented, and the tumor size should be evaluated using additional imaging studies. Immunohistochemical ...

Swiss IoT module maker u-blox is to phase out its loss-making cellular IoT business, the firm has said. The division has over 200 employees; jobs are expected to go with its closure. It made revenue ...

Two new cellular agriculture scale-up facilities have opened in the Netherlands, as the country works to strengthen its position as a global leader in the sector and invest in the future of food. The ...

The network is called Lunar Surface Communication System (LSCS), and it is basically a replica of the 4G/LTE cellular technology currently used on a very large scale by the humans of Earth.

(Reuters) - Johnson & Johnson said on Monday it would buy neurological drug maker Intra-Cellular Therapies for $14.6 billion, its biggest deal in more than two years, boosting its presence in the ...

Postoperative pathology revealed the tumor comprised spindle-shaped neoplastic cells and osteoclast-like giant cells, with significant cellular atypia and active mitoses (10/10 high-power fields), ...