Importantly, most of the CF gene therapy research is currently funded by charities such as the Cystic Fibrosis Trust, UK; Communication with CF patients and families about progress and ...

Boehringer Ingelheim (BI) and the UK Cystic Fibrosis Gene Therapy Consortium announced a global collaboration to develop a first-in-class, long-term therapy for patients with cystic fibrosis (CF).

Cystic fibrosis is a hereditary and lifelong disease that leads to mucus formation in the throat, difficulty breathing, reduced lung function, and often premature death. The disease is linked to ...

Dec. 10, 2024 — In a single IV injection, a gene therapy targeting cBIN1 can reverse the effects of heart failure and restore heart function in a large animal model. The therapy increases the ...

Nanoscope Therapeutics is on the brink of filing for FDA approval of what could be the first gene therapy for incurable eye disease retinitis pigmentosa (RP) that can be used regardless of ...

Objective: Conventional fine-needle aspiration biopsy (FNAB) for cystic thyroid nodules (CTNs) has a high rate of nondiagnostic and false-negative results. Ultrasound-guided FNAB (UG-FNAB ...

Spatial transcriptomics was combined with single-nucleus RNA sequencing to annotate healthy and fibrotic human livers, improving spatial resolution of hepatocytes and receptor-ligand interactions ...

This study introduces AdipoExpress, an eQTL meta-analysis of 2,344 subcutaneous adipose tissue samples, which triples the size of previous studies and expands the discovery of eQTLs colocalized ...

There is evidence that Crohn’s disease is genetic, though environmental factors may also be involved. Crohn’s disease is a type of inflammatory bowel disease (IBD) that causes inflammation in ...

If an equation can be rearranged into the form \(y = mx + c\), then its graph will be a straight line. In the above: \(x + y = 3\) can be rearranged as \(y = 3 - x\) (which can be re-written as ...

Background Newborn bloodspot screening (NBS) for cystic fibrosis (CF) was introduced across the UK in 2007 but the impact on clinical outcomes and health inequalities for children with CF is unclear.

What is a cystic hygroma? A cystic hygroma — or lymphangioma — is a birth defect that appears as a sac-like structure with a thin wall that most commonly occurs in the head and neck area of an infant.