Driver mutations are the pathophysiological hallmark of the disease, but the role of mutation clearance after transplantation is unclear. In patients with myelofibrosis, clearance of driver ...

Genome editing with CRISPR-Cas is often associated with the induction of mutations. However, a team of researchers from the Swiss University of Lausanne now shows that it can also be used to ...

Researchers in the group of Dr. Myriam Charpentier discovered a mutation in a gene in the legume Medicago truncatula that reprograms the signaling capacity of the plant so that it enhances ...

For 30 years, researchers have known that Huntington's is caused by an inherited mutation in the Huntingtin (HTT) gene, but they didn't know how the mutation causes brain cell death. A study ...

A mutation that causes an amino-acid substitution in a channel called CNGC15 in the plant cell’s nucleus boosts the formation of such endosymbiotic relationships. Studying ion channels in their ...

In early December 2024, a group of researchers published an article in the journal Science, entitled "A single mutation in bovine influenza H5N1 hemagglutinin switches specificity to human receptors".

A new mega-database of half a million mutations may flag new ways of treating genetic disease, scientists say. When you purchase through links on our site, we may earn an affiliate commission.

This means that the damage has multiple chances to generate harmful mutations, which can lead to cancer. While most known types of DNA damage are fixed by our cells' in-house DNA repair mechanisms ...

The Garvan team revealed that this is not the case -- rather, the critical trigger is mutations in 'rogue clone' B cells. "This discovery fundamentally changes our understanding of how infections ...

One of the earliest strains of bird flu isolated from a human in Texas shows a unique constellation of mutations that enable it to more easily replicate in human cells and cause more severe ...