Researchers at The Jackson Laboratory have discovered that certain genetic factors that predispose individuals to diabetes ...

The endoplasmic reticulum (ER) is a compartment (organelle) in eukaryotic cells that consists of membrane sacs called cisternae. Because of the bound ribosomes, the 'rough' ER is the site of ...

The intracellular bacterial pathogen Coxiella burnetii secretes an effector protein, CbEPF1, which manipulates LD metabolism ...

Study provides genome-wide insights into human islet stress responses and context-specific type 2 diabetes variant effects.

Researchers meticulously examined the gametogenesis of budding yeast, a process involving meiosis and spore formation, using live imaging techniques. Their findings revealed that during sporulation, ...

Discover how diabetes risk genes impair cellular resilience, making cells more vulnerable to stress and damage, contributing ...

Pacylex Pharmaceuticals Publishes a New Myristoylation Inhibitor Mechanism of Anti-Cancer Activity in Molecular Cancer Therapeutics ...

The cells in your pancreas, like people, can only handle so much stress before they start to break down. Certain stressors, ...

Gillham, SH, Cole, PL, Viggars, MR, Nolan, AH, Close, GL and Owens, DJ (2024) Comparative transcriptomics of broad-spectrum ...

The study suggests that certain antibiotics induce endoplasmic reticulum (ER) stress in colonic cells, thus diminishing mucus production. Based on this observation, the researchers conclude that ...

Previously, the research group revealed that autophagosome formation takes place on the endoplasmic reticulum membrane in close proximity to mitochondria within cells. They also discovered that ...