a new strategy for eliminating autoantigen-selected B cells and for treating early lymphoblastic leukemias and/or lymphomas was developed using CD19-specific mAbs that induce Fcγ receptor ...
Eledon Pharmaceuticals has a promising anti-CD40L antibody for organ rejection prevention in transplantation. Learn more ...
The latter consists of the phagocytosis of opsonized B-cells by neutrophils, monocytes and macrophages, which express the Fcγ Receptor. Moreover, RTX significantly decreases T-cell function, by ...
This medicine is designed to minimize binding to Fc-gamma (Fcγ) receptors on macrophages, helping the body’s immune cells detect, remain active longer and better fight tumors, while maintaining a ...
A sulfite allergy is caused by exposure to sulfur-based compounds naturally found in certain foods and used in certain food preservatives and additives. This can lead to allergy symptoms like wheezing ...
Compared with the other IgG subclasses, IgG4 has a negligible ability to activate the classic complement pathway, and its binding to Fcγ receptors is much lower than that of IgG1. IgG4 antibodies are ...
This review summarizes recent progress in both natural and engineered structural modifications of IgG antibodies, including allotypic variation, glycosylation, Fc engineering, and Fc gamma receptor ...
Correspondence to Dr H U Scherer, Department of Rheumatology, Leiden University Medical Centre, P.O. Box 9600 Leiden 2300 RC, The Netherlands; h.u.scherer{at}lumc.nl Objective To determine whether ...
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