San Francisco 49ers running back Isaac Guerendo is set to return from foot and hamstring injuries and play Monday vs. the ...

When it comes to injuries, the Detroit Lions haven't gotten a lot of good news this season. However, on their Friday practice ...

The Detroit Lions are gearing up for a playoff run that could be historic, and they just got some good news going into it.

The bad injury situation exacerbated for the 49ers during the week with multiple downgrades – Colton McKivitz, Charvarius ...

Last time the 49ers faced Detroit, they won but also gave up 31 points. And that was in the NFC Championship Game last season ...

The Detroit Lions can breath a sign of relief after getting some positive indicators ahead of the team's 49ers game.

A Christmas wish list for the Detroit Lions: what we want Santa to bring our football team this holiday season ...

Brian Branched moved from his safety position to slot cornerback in nickel packages Sunday to help the Detroit Lions' ...

The Lions opened Kalif Raymond's 21-day return-to-practice window but do not expect to have the return man for Monday's game ...

The San Francisco 49ers are 6-9 and out of playoff contention, but beat the Detroit Lions in the NFC championship game in ...

This isn't the same 49ers team the Lions lined up against 11 months ago, but Detroit is still treating it like a marquee game ...

ALLEN PARK -- Terrion Arnold was not spotted at Thursday’s practice after the Detroit Lions returned from a brief holiday ...