Results from DENALI Part 1b show an Objective Response Rate (ORR) of ~35% in response-evaluable, heavily-pretreated patients with Cyclin E1+ ...

Ovarian cancer is caused by a harmful ... fallopian tubes and they include low grade and high grade tumor types. These cancers should be treated with surgery, radiation, targeted therapy, and ...

Toxic effects for which a specific grade is not listed are generally assessed ... Although proteins remain the most common cancer biomarkers, other molecules, such as circulating cell-free tumour DNA, ...

Oral squamous cell carcinoma (OSCC) is an aggressive cancer, with prognosis influenced by clinical variables as well grading systems and perineural invasion (PNI), which are associated to poorer ...

Ovarian cancer has seen a significant shift in its treatment paradigm with the introduction of poly (ADP-ribose) polymerase (PARP) inhibitors, which are now standard in the maintenance setting ...

Traditional approaches to prostate cancer screening involve blood tests, MRI, and biopsies. However, in addition to being ...

Nearly half of patients with advanced ovarian cancer treated with first-line poly-ADP-ribose polymerase (PARP) inhibitors experienced recurrence in this real-world study, emphasizing the need for ...

evaluate these biomarkers in pre-clinical cancer models. Significant efforts are directed towards validating biomarkers for early prediction of treatment response, with the focus on new targeted ...

In contrast, the sensitivity of IFSH for predicting final surgical margin status was low, at 21.7%. This indicates that while ...

Toxicity was moderate: febrile neutropenia, grade 3 infection ... (fluorescence in situ hybridization [FISH] positive) ovarian cancer progressing under taxane/carboplatin chemotherapy or in ...

Research on the development, physiology and pathophysiology of reproductive disorders is important, as evidence suggests that many adult-onset diseases can be traced back to disruptions during early ...

A pioneering study has unveiled the Au-HN-1 nanosystem, a cutting-edge approach that promises to transform the diagnosis and treatment of tongue squamous cell carcinoma (TSCC). By harnessing gold ...