Clear cellular ovarian cancer is a rare subtype ... undifferentiated carcinoma and germ cell ovarian cancer. Image: Organoid or ‘live mini tumours’ of high grade serous ovarian cancer grown in ICR ...

Ovarian cancer, often called the silent killer, presents one of the most serious health threats women face globally. Its ...

Results from DENALI Part 1b show an Objective Response Rate (ORR) of ~35% in response-evaluable, heavily-pretreated patients with Cyclin E1+ ...

Avutometinib and defactinib target KRAS-mutated recurrent low-grade serous ovarian cancer, potentially becoming the first ... which is involved in cell growth and death. Furthermore, the NDA filing ...

SLFN11 is a BRCA independent biomarker for the response to platinum-based chemotherapy in high-grade serous ovarian cancer and clear cell ovarian carcinoma. Anticancer efficacy of KRASG12C ...

The most advanced development program, PARP inhibitor Senaparib (IMP4297), has been in clinical Phase II/III studies globally, including China, in ovarian cancer, small cell lung cancer and other ...

In lab-dish experiments, the sEVs specifically move towards and bind to DR5 and quickly killed cancer cell types that have high levels of DR5 expression, including melanoma, liver and ovarian ...

Luveltamab targets the cell surface protein folate ... in patients with platinum-resistant ovarian cancer, namely the phase 1 study at ASCO 2024. High-grade neutropenia was a concerning toxicity ...

Ovarian cancer is caused by a harmful ... fallopian tubes and they include low grade and high grade tumor types. These cancers should be treated with surgery, radiation, targeted therapy, and ...