Interstitial fibrosis (among myocytes) and perivascular fibrosis (surrounding the vessel walls). In addition to those, there are two dominant reasons why fibrosis may develop. Fibrosis may be ...

Fibrosis can be reactive (located at the interstitial space) or reparative (replaces dead myocytes) (Silver et al., 1990; Burstein and Nattel, 2008). It is important to note that, in contrast with the ...

Several observations from preclinical and short-term clinical studies support a role for sildenafil in the treatment of heart failure patients. The following discussion briefly considers each of ...

An imbalance in gene activity in two types of immune cells explains why lung fibrosis after a severe COVID-19 infection doesn ...

Figure 1. Overview of cellular steps leading to cardiac fibrosis. Following injury, cardiac fibroblasts are activated and transdifferentiated into myofibroblasts to replace dying cardiomyocytes. Dying ...

Learn about cystic fibrosis, a genetic disorder that affects the lungs, pancreas, and other organs, and how to treat and live with this chronic disease. 12 min read What Is Cystic Fibrosis? Cystic ...

The term dilated cardiomyopathy (DCM) refers to a spectrum of heterogeneous myocardial disorders that are characterized by ventricular dilation and depressed myocardial performance in the absence of ...