In a breakthrough for the advanced study of gut health, NUS scientists have developed a 3D microscopic version of the human ...

Solid tumors that originate in the deep internal organs, such as the pancreas, liver, and ovary, have poor prognoses due to the difficulties of diagnosing ...

Cells navigating in complex microenvironments frequently encounter narrow spaces that physically challenge migration.

Researchers have identified the molecular and cellular mechanisms that transform healthy stem cells into oral cancer at the earliest stages of the disease. Nearly 60,000 people are diagnosed with oral ...

Intestinal stem cells are multipotent adult stem cells, which in mammals reside in the base of the crypts of the adult intestine. Intestinal stem cells continuously self-renew by dividing and ...

We discuss the challenges such as immunosuppressive microenvironment, tumor heterogeneity, and physical barriers that limit CAR-T efficacy. Emerging strategies, such as logic-gated and dual-targeting ...

Intestinal villi (singular: villus)are tiny, finger-like projections that line the interior (lumen) of the small intestine. The primary function of villi is to absorb nutrients from food and transfer ...

PROX1+ cells in intestinal adenomas of ApcMin/+ mice expressed intestinal epithelial and CRC stem cell markers, and cells with high PROX1 expression could both self-renew tumor stem/progenitor cells ...

In the new study, Paz and her collaborators tested a stem cell therapy under development by SanBio. One month after rats had a stroke, the scientists injected the modified human stem cells into ...

Intestinal metaplasia (IM) occurs when the body replaces the cells that line the upper digestive tract (including the stomach and esophagus) with cells that line the intestines. When IM happens in ...