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Males with lupus nephritis had higher all-cause mortality and proportion of infection-related death compared to females.

REPEAT kidney biopsies may play an essential role in managing lupus nephritis, particularly for patients whose disease ...

Kezar’s decision to terminate the PALIZADE IIb trial comes after it was placed on a clinical hold due to four patient deaths.

2 Key Laboratory of Immune Response and Immunotherapy, Shanghai Institute of Immunity and Infection, Chinese Academy of Sciences, Shanghai, China 3 University of Chinese Academy of Sciences, Beijing, ...

Kezar Life Sciences announced the termination of Phase 2b PALIZADE clinical trial of zetomipzomib, an investigational therapy ...

particularly due to lupus nephritis (LN). The standard therapeutic approach involving mycophenolate mofetil, cyclophosphamide, and glucocorticoids has shown limitations due to cumulative toxicity and ...

Positive topline results were announced from a phase 3 study of obinutuzumab in patients with lupus nephritis. Obinutuzumab, a monoclonal antibody that targets the CD20 receptor on B-cells, is ...

Kezar was testing the treatment, zetomipzomib, in patients with active lupus nephritis, a type of kidney disease caused by lupus - where the body's immune system attacks its own cells and organs.

Now, the company has hit the brakes on its phase 2b study of the drug in lupus nephritis following four patient fatalities. An independent data monitoring committee (IDMC) recommended suspending ...

Swiss pharma giant Roche (ROG: SIX) has announced positive top-line results from the Phase III REGENCY study of Gazyva/Gazyvaro (obinutuzumab) in people with active lupus nephritis. The company noted ...