The potent extrafollicular B cell response and activated GZMK + CD8 T cells may form a vicious circle and unique ecosystem, which may underlie the pathogenesis in lupus kidney. These findings may ...

Neuropsychiatric systemic lupus erythematosus (NPSLE), or central nervous system lupus, can be challenging to diagnose ...

To date, treatment with NIM-1324 has reduced the production of interferon alpha in human peripheral blood mononuclear cells (PBMCs) from systemic lupus erythematosus (SLE) patients and provided ...

Neonatal lupus erythematosus is associated with cutaneous lesions, CHB, hepatic disease, and thrombocytopenia. IgG antibodies to Ro and/or La cross the placenta and participate in the development ...

Sept 30 (Reuters) - Kezar Life Sciences (KZR.O), opens new tab said on Monday it has paused a trial of its experimental drug for lupus to review safety data after four patients died in the mid ...

Now, the company has hit the brakes on its phase 2b study of the drug in lupus nephritis following four patient fatalities. An independent data monitoring committee (IDMC) recommended suspending ...

Genentech announced positive results from the Phase III study (REGENCY) of Gazyva (Obinutuzumab) for people with active lupus nephritis (LN). Gazyva is an engineered humanized monoclonal antibody ...

Sept 24 (Reuters) - Biogen (BIIB.O), opens new tab and Belgian partner UCB (UCB.BR), opens new tab said on Tuesday their experimental lupus treatment met the main goal of a late-stage trial in ...