targeting calpain-2 for people living with amyotrophic lateral sclerosis (ALS). With the clinical hold lifted, Amylyx is now working to open U.S. sites for screening, enrollment, and dosing.

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease that remains incurable, despite decades of basic and clinical research. Key stakeholders—including the US National ...

Owing to the heterogeneous nature of amyotrophic lateral sclerosis (ALS), panels of protein biomarkers derived from cerebrospinal fluid and blood may be most valuable for generating an accurate ...

Amyotrophic lateral sclerosis (ALS) is an adult-onset neurodegenerative disease characterized by loss of motor neurons in the brain and spinal cord. Mutations in the gene encoding superoxide ...

Explore the role of preclinical MRI in studying neurological diseases, with a focus on advanced cellular and molecular ...

A recent study investigated muscle function in people with hip ... Ultra-Powered MRI Scans Show Damage to Brain's 'Control Center' Is Behind Long-Lasting COVID-19 Symptoms Oct. 8, 2024 — Damage ...

Jan. 22, 2025 — Thermal sensations are consciously differentiated as hot or cold by the brain; however, the neural mechanism that enables this differentiation is not well understood. To address ...

Relapsing-remitting multiple sclerosis is a type of multiple sclerosis ... making it difficult for your brain to communicate with the rest of your body. Continue reading to learn how RRMS compares ...

The human brain, as the seat of mental life—from the most complicated intellectual processes down to routine and unconscious bodily control—is necessarily enormously complex. The largest part ...

Amyotrophic lateral sclerosis (ALS, also known as motor neuron disease) is a relentlessly progressive and fatal neurodegenerative disorder caused by motor neuron death in the brain and spinal cord.

Memory is a continually unfolding process. Initial details of an experience take shape in memory; the brain’s representation of that information then changes over time. With subsequent ...