Researchers create new compound to potentially treat negative and positive symptoms of schizophrenia
We often think about diseases in terms of the symptoms they present. A cold might give you the sniffles or even GI distress, while malaria can give you fever, chills, or nausea, for example. These ...
Nature6y
Reducing glutamate signaling pays off in fragile X
The findings point the way to treatment options targeting group 1 metabotropic glutamate receptors. This study is a major step toward the ultimate goal of treating fragile X syndrome (FXS), an ...
Nature16d
Long-term depression in the CNS
Most studies have focused on forms of LTD that are triggered by synaptic activation of either NMDARs (N-methyl-D-aspartate receptors) or metabotropic glutamate receptors (mGluRs). Converging ...