A research team from the University of California, Irvine has revealed a previously unknown mechanism that triggers an inflammatory immune response in cells when their DNA is damaged. This ...

The paper entitled "Plural molecular and cellular mechanisms of pore domain KCNQ2 encephalopathy" by Abreo et al. is a complex and integrated paper that is well-written with a focus on a single gene ...

The paper investigates a potential cause of a type of severe epilepsy that develops in early life because of a defect in a gene called KCNQ2. The significance is fundamental because it substantially ...

They obtained biopsies from volunteers to investigate the molecular mechanism behind this. “When you did the skin biopsy with the punch in the athletes, it was crunching [like] an apple, like it felt ...

Activating agents enable the efficient preparation of organozinc complexes from zinc metal and organohalides, but their mechanisms had been obscured by the heterogeneous nature of these systems.

Thus, despite these findings, the mechanisms associated with hemostasis disruption ... Activated platelets degranulate and secrete damage-associated molecular patterns (DAMPs), such as HMGB1 (high ...

New research identifies key cellular mechanism driving Alzheimer's disease. ScienceDaily . Retrieved January 19, 2025 from www.sciencedaily.com / releases / 2024 / 12 / 241223135051.htm ...

Employing gene-technological methods such as CRISPR-Cas9 genome editing, they were able to establish the molecular mechanisms of how mitochondria counteract cellular NAD decline. "Decreased ...

The Supporting Information is available free of charge at https://pubs.acs.org/doi/10.1021/acs.macromol.4c01893.