Muscarinic receptors are involved with neurotransmission via acetylcholine and glutamate, and are hypothesised to be dysfunctional in schizophrenia. Most drugs developed to treat schizophrenia to ...

Dr. Heh-In Im at the Center for Brain Disorders of the Korea Institute of Science and Technology (KIST) has identified a novel brain region and neural mechanism involved in regulating nicotine ...

For part 3 of our interview with Katie Abouzahr, MD, Johnson & Johnson Innovative Medicine, we discuss the favorable safety ...

In preliminary studies, we discovered that selected typical and atypical antipsychotic drugs interacted with virtually every biogenic amine receptor tested, in confirmation of many prior studies ...

Receptor pharmacology is the study of the interactions of receptors with drugs/pharmaceuticals and other xenobiotics. A basic tenet of receptor pharmacology is that a drug’s effect is directly ...

The Vivacity-MG3 study is currently in its open-label extension phase, which is investigating the longer-term safety and ...

Nicotine withdrawal induces behavioral symptoms such as tremors and shaking. Suppressing striatal cholinergic interneurons or administering the muscarinic antagonist Procyclidine significantly reduces ...

Expert Rev Endocrinol Metab. 2010;5(5):653-662.