shunting of blood continues and results in persistent pulmonary hypertension of the neonate (PPHN), causing severe hypoxemia.

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Inhaled NO therapy is an effective form of treatment in acute conditions, such as ARDS and PPHN; it is particularly effective in increasing oxygen saturation and decreasing pulmonary artery pressure.

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A study was conducted to determine the efficacy of several vasodilators for treatment of persistent pulmonary hypertension in newborns.

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