Vertex has just filed for approval of Kalydeco for CF patients aged 18 and older who have the R117H mutation, the most common residual function mutation, which could add another 300 patients to ...

The agreement also offers expanded access to Kalydeco (ivacaftor) to include people aged 18 years and older who have the R117H mutation and those patients aged 12 months and older who have one of ...

Driver mutations are the pathophysiological hallmark of the disease, but the role of mutation clearance after transplantation is unclear. In patients with myelofibrosis, clearance of driver ...

To achieve this, the donated cells must replicate again and again — and again. It’s a cycle that might put recipients at risk if a new, potentially harmful mutation arises or if a mutation present in ...

The first severe case of bird flu in the U.S. is showing signs of mutation, stoking fears that the virus could become more transmissible among humans, the U.S. Centers for Disease Control and ...

Genetic sequences of H5N1 bird flu viruses collected from a person in Louisiana who became severely ill show signs of development of several mutations thought to affect the virus’ ability to ...

Scientists are investigating a mutation in the H5N1 avian influenza virus, raising concerns about a potential human pandemic. A study revealed that a single mutation, Q226L, enhances the virus's ...

The second pair, HumVar 3, consists of all the 13,032 human disease-causing mutations from UniProt and 8,946 human nonsynonymous single-nucleotide polymorphisms (nsSNPs) without annotated ...

Now, on this morning in September 2021, Linde would find out if she had inherited the same vile genetic mutation. She had a bad feeling. She and her mother had been so alike. Allison had been a ...

(Reuters) - The U.S. Centers for Disease Control and Prevention said on Thursday its analysis of samples from the first severe case of bird flu in the country last week showed mutations not seen ...

But there is no sign that mutations are widespread in nature. By Benjamin Mueller After someone in southwest Louisiana was hospitalized with a severe case of bird flu, the first such illness ...